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1

Early phase II trial of oral vorinostat in relapsed or refractory breast, colorectal, or non-small cell lung cancer

Johan Vansteenkiste, Eric Van Cutsem, Herlinde Dumez, Cong Chen, Justin L. Ricker, Sophia S. Randolph, Patrick Schöffski

Journal:

Investigational New Drugs

Year:

2008

Language:

english

File:

PDF, 110 KB

english, 2008

2

Gastrointestinal Stromal Tumors II: Medical Oncology and Tumor Response Assessment

Robert S. Benjamin, Maria Debiec-Rychter, Axel Le Cesne, Stefan Sleijfer, George D. Demetri, Heikki Joensuu, Patrick Schöffski, Andrés Poveda

Journal:

Seminars in Oncology

Year:

2009

Language:

english

File:

PDF, 696 KB

english, 2009

3

Simultaneous determination of AMN107 and Imatinib (Gleevec®, Glivec®, STI571) in cultured tumour cells using an isocratic high-performance liquid chromatography procedure with UV detection

Gunther Guetens, Hans Prenen, Gert De Boeck, Allan van Oosterom, Patrick Schöffski, Martin Highley, Ernst A. de Bruijn

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 282 KB

english, 2007

4

Adaptation and performance of an immuno-PCR assay for the quantification of Aviscumine in patient plasma samples

Michael Adler, Martin Langer, Klaus Witthohn, Karin Wilhelm-Ogunbiyi, Patrick Schöffski, Pierre Fumoleau, Christof M. Niemeyer

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2005

Language:

english

File:

PDF, 548 KB

english, 2005

5

Determination of 9-nitrocamptothecin and its metabolite 9-aminocamptothecin in human plasma using high-performance liquid chromatography with ultraviolet and fluorescence detection

Nadja E Schoemaker, Hilde Rosing, Sindy Jansen, Patrick Schöffski, Jinee Rizzo, Jan H.M Schellens, Jos H Beijnen

Journal:

Journal of Chromatography B

Year:

2002

Language:

english

File:

PDF, 243 KB

english, 2002

6

Quantification of hepatic thrombopoietin mRNA transcripts in patients with chronic liver diseases shows maintained gene expression in different etiologies of liver cirrhosis

Frank Tacke, Christian Trautwein, Shourong Zhao, Michael Andreeff, Michael P. Manns, Arnold Ganser, Patrick Schöffski

Journal:

Liver International

Year:

2002

Language:

english

File:

PDF, 332 KB

english, 2002

7

Thrombopoietin serum levels are elevated in patients with hepatitis B/C infection compared to other causes of chronic liver disease

Patrick Schöffski, Frank Tacke, Christian Trautwein, Michael Uwe Martin, Martin Caselitz, Hartmut Hecker, Michael Peter Manns, Arnold Ganser

Journal:

Liver International

Year:

2002

Language:

english

File:

PDF, 89 KB

english, 2002

8

Intrinsic cell memory reinforces myogenic commitment of pericyte-derived iPSCs

Mattia Quattrocelli, Giacomo Palazzolo, Giuseppe Floris, Patrick Schöffski, Luigi Anastasia, Aldo Orlacchio, Thierry Vandendriessche, Marinee KL Chuah, Giulio Cossu, Catherine Verfaillie, Maurilio Sam

Journal:

The Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 958 KB

english, 2011

9

Development of an optimal pharmacokinetic sampling schedule for rubitecan administered orally in a daily times five schedule

Nadja E. Schoemaker, Ron A. Mathôt, Patrick Schöffski, Hilde Rosing, Jan H. Schellens, Jos H. Beijnen

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2002

Language:

english

File:

PDF, 220 KB

english, 2002

10

A phase I and pharmacologic study of the matrix metalloproteinase inhibitor CP-471,358 in patients with advanced solid tumors

André Planting, Ate van der Gaast, Patrick Schöffski, Michele Bartkowski, Coleta Verheij, Dennis Noe, Karen Ferrante, Jaap Verweij

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2005

Language:

english

File:

PDF, 219 KB

english, 2005

11

Efficacy and safety of motesanib, an oral inhibitor of VEGF, PDGF, and Kit receptors, in patients with imatinib-resistant gastrointestinal stromal tumors

Robert S. Benjamin, Patrick Schöffski, Jörg Thomas Hartmann, Allan Van Oosterom, Binh Nguyen Bui, Justus Duyster, Scott Schuetze, Jean-Yves Blay, Peter Reichardt, Lee S. Rosen, Keith Skubitz, Sheryl M

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 438 KB

english, 2011

12

A phase I dose-escalating study of ES-285, a marine sphingolipid-derived compound, with repeat dose administration in patients with advanced solid tumors

Eduardo Vilar, Viktor Grünwald, Patrick Schöffski, Harald Singer, Ramon Salazar, Jose Luis Iglesias, Esther Casado, Martin Cullell-Young, Jose Baselga, Josep Tabernero

Journal:

Investigational New Drugs

Year:

2012

Language:

english

File:

PDF, 131 KB

english, 2012

13

A phase II study of the efficacy and safety of AMG 102 in patients with metastatic renal cell carcinoma

Patrick Schöffski, Jorge A. Garcia, Walter M. Stadler, Thierry Gil, Eric Jonasch, Scott T. Tagawa, Melanie Smitt, Xinqun Yang, Kelly S. Oliner, Abraham Anderson, Min Zhu, Fairooz Kabbinavar

Journal:

BJU International

Year:

2011

Language:

english

File:

PDF, 456 KB

english, 2011

14

An Economic Evaluation of Cetuximab Combined with Radiotherapy for Patients with Locally Advanced Head and Neck Cancer in Belgium, France, Italy, Switzerland, and the United Kingdom

Ben Brown, Alexander Diamantopoulos, Jacques Bernier, Patrick Schöffski, Klaus Hieke, Lorenzo Mantovani, Robert Launois, Ingolf Griebsch, Paul Robinson

Journal:

Value in Health

Year:

2008

Language:

english

File:

PDF, 168 KB

english, 2008

15

Gastrointestinal Stromal Tumors I: Pathology, Pathobiology, Primary Therapy, and Surgical Issues

Peter Reichardt, Pancras C.W. Hogendoorn, Elena Tamborini, Massimo Loda, Alessandro Gronchi, Andrés Poveda, Patrick Schöffski

Journal:

Seminars in Oncology

Year:

2009

Language:

english

File:

PDF, 2.38 MB

english, 2009

16

Patterns of Care, Prognosis, and Survival in Patients with Metastatic Gastrointestinal Stromal Tumors (GIST) Refractory to First-Line Imatinib and Second-Line Sunitinib

Antoine Italiano, Angela Cioffi, Paola Coco, Robert G. Maki, Patrick Schöffski, Piotr Rutkowski, Axel Le Cesne, Florence Duffaud, Antoine Adenis, Nicolas Isambert, Emmanuelle Bompas, Jean-Yves Blay, P

Journal:

Annals of Surgical Oncology

Year:

2012

Language:

english

File:

PDF, 384 KB

english, 2012

17

Does a patient’s self-reported health-related quality of life predict survival beyond key biomedical data in advanced colorectal cancer?

Fabio Efficace, Andrew Bottomley, Corneel Coens, Kristel Van Steen, Thierry Conroy, Patrick Schöffski, Hans Schmoll, Eric Van Cutsem, Claus-Henning Köhne

Journal:

European Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 141 KB

english, 2006

18

Corrigendum to “Does a patient’s self-reported health-related quality of life predict survival beyond key biomedical data in advanced colorectal cancer?” [Eur. J. Cancer 42 (2006) 42–49]

Fabio Efficace, Andrew Bottomley, Corneel Coens, Kristel Van Steen, Thierry Conroy, Patrick Schöffski, Hans Schmoll, Eric Van Cutsem, Claus-Henning Köhne

Journal:

European Journal of Cancer

Year:

2007

Language:

english

File:

PDF, 95 KB

english, 2007

19

Using the continual reassessment method: Lessons Learned from an EORTC phase I dose finding study

Xavier Paoletti, Benoît Baron, Patrick Schöffski, Pierre Fumoleau, Denis Lacombe, Sandrine Marreaud, Richard Sylvester

Journal:

European Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 185 KB

english, 2006

20

Multicentric parallel phase II trial of the polo-like kinase 1 inhibitor BI 2536 in patients with advanced head and neck cancer, breast cancer, ovarian cancer, soft tissue sarcoma and melanoma. The first protocol of the European Organization for Research and Treatment of Cancer (EORTC) Network Of Core Institutes (NOCI)

Patrick Schöffski, Jean-Yves Blay, Jacques De Greve, Etienne Brain, Jean-Pascal Machiels, Jean-Charles Soria, Stefan Sleijfer, Pascal Wolter, Isabelle Ray-Coquard, Christel Fontaine, Gerd Munzert, Hol

Journal:

European Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 657 KB

english, 2010

21

The preclinical and clinical activity of aviscumine: A potential anticancer drug

Heinz Zwierzina, Lothar Bergmann, Heiner Fiebig, Steinar Aamdal, Patrick Schöffski, Klaus Witthohn, Hans Lentzen

Journal:

European Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 290 KB

english, 2011

22

Phase I, open-label, multicentre, dose-escalation, pharmacokinetic and pharmacodynamic trial of the oral aurora kinase inhibitor PF-03814735 in advanced solid tumours

Patrick Schöffski, Suzanne F. Jones, Herlinde Dumez, Jeffrey R. Infante, Elke Van Mieghem, Camilla Fowst, Paola Gerletti, Huiping Xu, John L. Jakubczak, Patricia A. English, Kristen J. Pierce, Howard

Journal:

European Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 215 KB

english, 2011

23

A phase I, dose-escalation study of the novel Polo-like kinase inhibitor volasertib (BI 6727) in patients with advanced solid tumours

Patrick Schöffski, Ahmad Awada, Herlinde Dumez, Thierry Gil, Sylvie Bartholomeus, Pascal Wolter, Martine Taton, Holger Fritsch, Patricia Glomb, Gerd Munzert

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 245 KB

english, 2012

24

Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial

Winette TA van der Graaf, Jean-Yves Blay, Sant P Chawla, Dong-Wan Kim, Binh Bui-Nguyen, Paolo G Casali, Patrick Schöffski, Massimo Aglietta, Arthur P Staddon, Yasuo Beppu, Axel Le Cesne, Hans Gelderbl

Journal:

Year:

2012

Language:

english

File:

PDF, 292 KB

english, 2012

25

Activity of eribulin mesylate in patients with soft-tissue sarcoma: a phase 2 study in four independent histological subtypes

Patrick Schöffski, Isabelle Laure Ray-Coquard, Angela Cioffi, Nguyen Bin Bui, Sebastian Bauer, Joerg Thomas Hartmann, Anders Krarup-Hansen, Viktor Grünwald, Raf Sciot, Herlinde Dumez, Jean-Yves Blay,

Journal:

The Lancet Oncology

Year:

2011

Language:

english

File:

PDF, 138 KB

english, 2011

26

A retrospective analysis of antitumour activity with trabectedin in translocation-related sarcomas

Axel Le Cesne, Sara Cresta, Robert G. Maki, Jean Yves Blay, Jaap Verweij, Andrés Poveda, Paolo G. Casali, Carme Balaña, Patrick Schöffski, Federica Grosso, Pilar Lardelli, Antonio Nieto, Vicente Alfar

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 708 KB

english, 2012

27

Ghrelin in chronic liver disease

Frank Tacke, Georg Brabant, Elmar Kruck, Rüdiger Horn, Patrick Schöffski, Hartmut Hecker, Michael P Manns, Christian Trautwein

Journal:

Journal of Hepatology

Year:

2003

Language:

english

File:

PDF, 259 KB

english, 2003

28

Thrombopoietin serum levels are elevated in patients with chronic virus hepatitis and controlled on a post-transcriptional level

Frank Tacke, Patrick Schoffski, Arnold Ganser, Michael P. Manns, Christian Trautwein

Journal:

Journal of Hepatology

Year:

2002

Language:

english

File:

PDF, 335 KB

english, 2002

29

Erythropoietin plasma levels are elevated in chronic liver disease and correlate with anemia, liver dysfunction, bleeding episodes and interleukin-6

Frank Tacke, Patrick Schoffski, Arnold Ganser, Michael P. Manns, Christian Trautwein

Journal:

Journal of Hepatology

Year:

2002

Language:

english

File:

PDF, 117 KB

english, 2002

30

Promoting role of cholecystokinin 2 receptor (CCK2R) in gastrointestinal stromal tumour pathogenesis

Quattrone, Anna, Dewaele, Barbara, Wozniak, Agnieszka, Bauters, Marijke, Vanspauwen, Vanessa, Floris, Giuseppe, Schöffski, Patrick, Chibon, Frederic, Coindre, Jean-Michel, Sciot, Raf, Debiec-Rychter,

Journal:

The Journal of Pathology

Year:

2012

Language:

english

File:

PDF, 3.77 MB

english, 2012

31

Intestinal Neurofibromatosis Is a Subtype of Familial GIST and Results From a Dominant Activating Mutation in PDGFRA

Thomas de Raedt, Jan Cools, Maria Debiec–Rychter, Hilde Brems, Nicole Mentens, Raf Sciot, Jacques Himpens, Ivo de Wever, Patrick Schöffski, Peter Marynen, Eric Legius

Journal:

Gastroenterology

Year:

2006

Language:

english

File:

PDF, 1.07 MB

english, 2006

32

Bendamustine

Patrick Schöffski, Arnold Ganser

Journal:

Year:

2001

Language:

english

File:

PDF, 94 KB

english, 2001

33

Cetuximab

Patrick Schöffski, Claus-Henning Könne

Journal:

Year:

2004

Language:

english

File:

PDF, 49 KB

english, 2004

34

Capecitabine/Oxaliplatin, a Safe and Active First-Line Regimen for Older Patients Metastatic Colorectal Cancer: Post Hoc Analysis of a Large Phase II Study

Chris J. Twelves, Charles A. Butts, Jim Cassidy, Thierry Conroy, Filippo de Braud, Eduardo Díaz-Rubio, Josep M. Tabernero, Patrick Schöffski, Arie Figer, René Brunet, Johannes Grossmann, Alberto F. So

Journal:

Clinical Colorectal Cancer

Year:

2005

Language:

english

File:

PDF, 887 KB

english, 2005

35

A Possible Role for MicroRNA-141 Down-Regulation in Sunitinib Resistant Metastatic Clear Cell Renal Cell Carcinoma Through Induction of Epithelial-to-Mesenchymal Transition and Hypoxia Resistance

Berkers, Joost, Govaere, Olivier, Wolter, Pascal, Beuselinck, Benoit, Schöffski, Patrick, van Kempen, Léon C., Albersen, Maarten, Van den Oord, Joost, Roskams, Tania, Swinnen, Johan, Joniau, Steven, V

Journal:

The Journal of Urology

Year:

2013

Language:

english

File:

PDF, 2.26 MB

english, 2013

36

Impact of tumor chronology and tumor biology on lymph node metastasis in breast cancer

Smeets, Ann, Ryckx, Andries, Belmans, Ann, Wildiers, Hans, Neven, Patrick, Floris, Giuseppe, Schöffski, Patrick, Christiaens, Marie-Rose

Journal:

Year:

2013

Language:

english

File:

PDF, 242 KB

english, 2013

37

Soft Tissue Sarcoma: An Update on Systemic Treatment Options for Patients with Advanced Disease

Schöffski, Patrick, Cornillie, Jasmien, Wozniak, Agnieszka, Li, Haifu, Hompes, Daphne

Journal:

Oncology Research and Treatment

Year:

2014

Language:

english

File:

PDF, 114 KB

english, 2014

38

Prognostic factors in adolescents and young adults (AYA) with high risk soft tissue sarcoma (STS) treated by adjuvant chemotherapy: A study based on pooled European Organisation for Research and Treatment of Cancer (EORTC) clinical trials 62771 and 62931

Kasper, Bernd, Ouali, Monia, van Glabbeke, Martine, Blay, Jean-Yves, Bramwell, Vivien H.C., Woll, Penella J., Hohenberger, Peter, Schöffski, Patrick

Journal:

European Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 321 KB

english, 2013

39

The effect of baseline morphology and its change during treatment on the accuracy of Response Evaluation Criteria in Solid Tumours in assessment of liver metastases

Schiavon, Gaia, Ruggiero, Alessandro, Bekers, Dave J., Barry, Peter A., Sleijfer, Stefan, Kloth, Jaqueline, Krestin, Gabriel P., Schöffski, Patrick, Verweij, Jaap, Mathijssen, Ron H.J.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

40

International expert opinion on patient-tailored management of soft tissue sarcomas

Blay, Jean-Yves, Sleijfer, Stefan, Schöffski, Patrick, Kawai, Akira, Brodowicz, Thomas, Demetri, George D., Maki, Robert G.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 612 KB

english, 2014

41

Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial

Judson, Ian, Verweij, Jaap, Gelderblom, Hans, Hartmann, Jörg T, Schöffski, Patrick, Blay, Jean-Yves, Kerst, J Martijn, Sufliarsky, Josef, Whelan, Jeremy, Hohenberger, Peter, Krarup-Hansen, Anders, Alc

Journal:

The Lancet Oncology

Year:

2014

Language:

english

File:

PDF, 320 KB

english, 2014

42

Bilateral testicular tumours: Prevalence and clinical implications

Bokemeyer, Carsten, Schmoll, Hans-Joachim, Schöffski, Patrick, Harstrick, Andreas, Bading, Margrit, Poliwoda, Hubert

Journal:

European Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 315 KB

english, 1993

43

The more you look, the more you find: challenging results on FDG-PET CT in a patient with neurofibromatosis type I

Patrick Schöffski,Christophe M Deroose,Olivier Gheysens,Nele Lips…

Journal:

BMC Medical Imaging

Year:

2014

Language:

english

File:

PDF, 210 KB

english, 2014

44

Implications of Mutational Analysis for the Management of Patients With Gastrointestinal Stromal Tumors and the Application of Targeted Therapies

Wozniak, Agnieszka, Floris, Giuseppe, Debiec-Rychter, Maria, Sciot, Raf, Schöffski, Patrick

Journal:

Cancer Investigation

Year:

2010

Language:

english

File:

PDF, 416 KB

english, 2010

45

Targeted therapies in the treatment of GIST: Adverse events and maximising the benefits of sunitinib through proactive therapy management

Wolter, Pascal, Schöffski, Patrick

Journal:

Acta Oncologica

Year:

2010

Language:

english

File:

PDF, 121 KB

english, 2010

46

Frequent mono-allelic loss associated with deficient PTEN expression in imatinib-resistant gastrointestinal stromal tumors

Quattrone, Anna, Wozniak, Agnieszka, Dewaele, Barbara, Floris, Giuseppe, Vanspauwen, Vanessa, Van Looy, Thomas, Schöffski, Patrick, Rutkowski, Piotr, Sciot, Raf, Debiec-Rychter, Maria

Journal:

Modern Pathology

Year:

2014

Language:

english

File:

PDF, 459 KB

english, 2014

47

Clinical impact of trabectedin (ecteinascidin-743) in advanced/metastatic soft tissue sarcoma

Schöffski, Patrick, Dumez, Herlinde, Wolter, Pascal, Stefan, Cristiana, Wozniak, Agnieszka, Jimeno, Jose, Van Oosterom, Allan T

Journal:

Expert Opinion on Pharmacotherapy

Year:

2008

Language:

english

File:

PDF, 195 KB

english, 2008

48

Shrinkage of Thyroid Volume in Sunitinib-Treated Patients with Renal-Cell Carcinoma: A Potential Marker of Irreversible Thyroid Dysfunction?

Rogiers, Aljosja, Wolter, Pascal, de Beeck, Katya Op, Thijs, Marleen, Decallonne, Brigitte, Schöffski, Patrick

Journal:

Year:

2010

Language:

english

File:

PDF, 6.61 MB

english, 2010

49

Clinical Response of Renal Cell Carcinoma to Dexamethasone

Schöffski, Patrick, Wolter, Pascal, Vandenborre, Katherine, Haustermans, Karin

Journal:

Cancer Investigation

Year:

2009

Language:

english

File:

PDF, 1.22 MB

english, 2009

50

Pazopanib, a Receptor Tyrosine Kinase Inhibitor, Suppresses Tumor Growth through Angiogenesis in Dedifferentiated Liposarcoma Xenograft Models

Li, Haifu, Wozniak, Agnieszka, Sciot, Raf, Cornillie, Jasmien, Wellens, Jasmien, Van Looy, Thomas, Vanleeuw, Ulla, Stas, Marguerite, Hompes, Daphne, Debiec-Rychter, Maria, Schöffski, Patrick

Journal:

Translational Oncology

Year:

2014

Language:

english

File:

PDF, 781 KB

english, 2014